matlab simpower systems Search Results


simpower system toolbox  (MathWorks Inc)
96
MathWorks Inc simpower system toolbox
Simpower System Toolbox, supplied by MathWorks Inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 96 stars, based on 1 article reviews
simpower system toolbox - by Bioz Stars, 2026-06
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matlab simpower systems toolbox  (MathWorks Inc)
96
MathWorks Inc matlab simpower systems toolbox
Matlab Simpower Systems Toolbox, supplied by MathWorks Inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/matlab simpower systems toolbox/product/MathWorks Inc
Average 96 stars, based on 1 article reviews
matlab simpower systems toolbox - by Bioz Stars, 2026-06
96/100 stars
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bile acid simpops  (DILIsym Services Inc)
90
DILIsym Services Inc bile acid simpops
Predicted maximum hepatic accumulation of CDCA and LCA species and DILI responses (i.e., minimum hepatic ATP, minimum viable liver mass, maximum serum ALT) post-dose in human <t>SimPops</t> at oral doses of 200 (green triangle), 400 (blue circle), or 600 (red diamond) mg/day TGZ for 6months (A), and rat SimPops at oral doses of 5 (blue circle) or 25 (red diamond) mg/kg/day for 6months (B).
Bile Acid Simpops, supplied by DILIsym Services Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/bile acid simpops/product/DILIsym Services Inc
Average 90 stars, based on 1 article reviews
bile acid simpops - by Bioz Stars, 2026-06
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system toolbox  (MathWorks Inc)
93
MathWorks Inc system toolbox
Predicted maximum hepatic accumulation of CDCA and LCA species and DILI responses (i.e., minimum hepatic ATP, minimum viable liver mass, maximum serum ALT) post-dose in human <t>SimPops</t> at oral doses of 200 (green triangle), 400 (blue circle), or 600 (red diamond) mg/day TGZ for 6months (A), and rat SimPops at oral doses of 5 (blue circle) or 25 (red diamond) mg/kg/day for 6months (B).
System Toolbox, supplied by MathWorks Inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/system toolbox/product/MathWorks Inc
Average 93 stars, based on 1 article reviews
system toolbox - by Bioz Stars, 2026-06
93/100 stars
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Predicted maximum hepatic accumulation of CDCA and LCA species and DILI responses (i.e., minimum hepatic ATP, minimum viable liver mass, maximum serum ALT) post-dose in human SimPops at oral doses of 200 (green triangle), 400 (blue circle), or 600 (red diamond) mg/day TGZ for 6months (A), and rat SimPops at oral doses of 5 (blue circle) or 25 (red diamond) mg/kg/day for 6months (B).

Journal: Clinical pharmacology and therapeutics

Article Title: Systems Pharmacology Modeling Predicts Delayed Presentation and Species Differences in Bile Acid-Mediated Troglitazone Hepatotoxicity

doi: 10.1038/clpt.2014.158

Figure Lengend Snippet: Predicted maximum hepatic accumulation of CDCA and LCA species and DILI responses (i.e., minimum hepatic ATP, minimum viable liver mass, maximum serum ALT) post-dose in human SimPops at oral doses of 200 (green triangle), 400 (blue circle), or 600 (red diamond) mg/day TGZ for 6months (A), and rat SimPops at oral doses of 5 (blue circle) or 25 (red diamond) mg/kg/day for 6months (B).

Article Snippet: Human (n=331) and rat (n=191) population samples with variability in 10 (human) or 11 (rat) parameters in the BA homeostasis sub-model (Bile Acid SimPops) were constructed previously within DILIsym using the genetic algorithm in MATLAB ; these Bile Acid SimPops are system-specific, and thus the same Bile Acid SimPops are used to simulate hepatotoxic effects of different compounds.

Techniques:

Summary of troglitazone (TGZ)-mediated hepatotoxicity in human SimPops and clinical trials.

Journal: Clinical pharmacology and therapeutics

Article Title: Systems Pharmacology Modeling Predicts Delayed Presentation and Species Differences in Bile Acid-Mediated Troglitazone Hepatotoxicity

doi: 10.1038/clpt.2014.158

Figure Lengend Snippet: Summary of troglitazone (TGZ)-mediated hepatotoxicity in human SimPops and clinical trials.

Article Snippet: Human (n=331) and rat (n=191) population samples with variability in 10 (human) or 11 (rat) parameters in the BA homeostasis sub-model (Bile Acid SimPops) were constructed previously within DILIsym using the genetic algorithm in MATLAB ; these Bile Acid SimPops are system-specific, and thus the same Bile Acid SimPops are used to simulate hepatotoxic effects of different compounds.

Techniques:

In human SimPops administered 400 (A) or 600 (B) mg/day troglitazone (TGZ) for 6months, individuals with serum ALT elevations > 3× ULN (n=10 at 400mg/day; n=17 at 600mg/day) are presented. One individual at 400mg/day and two individuals at 600mg/day lost >85% of viable liver mass and was classified as dead.

Journal: Clinical pharmacology and therapeutics

Article Title: Systems Pharmacology Modeling Predicts Delayed Presentation and Species Differences in Bile Acid-Mediated Troglitazone Hepatotoxicity

doi: 10.1038/clpt.2014.158

Figure Lengend Snippet: In human SimPops administered 400 (A) or 600 (B) mg/day troglitazone (TGZ) for 6months, individuals with serum ALT elevations > 3× ULN (n=10 at 400mg/day; n=17 at 600mg/day) are presented. One individual at 400mg/day and two individuals at 600mg/day lost >85% of viable liver mass and was classified as dead.

Article Snippet: Human (n=331) and rat (n=191) population samples with variability in 10 (human) or 11 (rat) parameters in the BA homeostasis sub-model (Bile Acid SimPops) were constructed previously within DILIsym using the genetic algorithm in MATLAB ; these Bile Acid SimPops are system-specific, and thus the same Bile Acid SimPops are used to simulate hepatotoxic effects of different compounds.

Techniques:

Inhibition constants for BSEP, MRP4, and NTCP were altered 10-fold in either direction of the values measured in isolated transport systems . Predicted maximum serum ALT concentrations in human and rat SimPops after an oral dose of 600mg/day and 5 mg/kg/day troglitazone (TGZ), respectively, for 1month are presented. Dashed lines represent 3× baseline ALT in human (90 U/L) and rat (63 U/L) SimPops.

Journal: Clinical pharmacology and therapeutics

Article Title: Systems Pharmacology Modeling Predicts Delayed Presentation and Species Differences in Bile Acid-Mediated Troglitazone Hepatotoxicity

doi: 10.1038/clpt.2014.158

Figure Lengend Snippet: Inhibition constants for BSEP, MRP4, and NTCP were altered 10-fold in either direction of the values measured in isolated transport systems . Predicted maximum serum ALT concentrations in human and rat SimPops after an oral dose of 600mg/day and 5 mg/kg/day troglitazone (TGZ), respectively, for 1month are presented. Dashed lines represent 3× baseline ALT in human (90 U/L) and rat (63 U/L) SimPops.

Article Snippet: Human (n=331) and rat (n=191) population samples with variability in 10 (human) or 11 (rat) parameters in the BA homeostasis sub-model (Bile Acid SimPops) were constructed previously within DILIsym using the genetic algorithm in MATLAB ; these Bile Acid SimPops are system-specific, and thus the same Bile Acid SimPops are used to simulate hepatotoxic effects of different compounds.

Techniques: Inhibition, Isolation